Construção e validação de conteúdo de instrumento de autoavaliação da qualidade do cuidado em instituição de longa permanência para pessoas idosas / Development and content validation for a self-assessment instrument of care quality in long-term care facilities for older adults

Resumo Objetivo Desenvolver e realizar a validação de conteúdo de um instrumento de autoavaliação da qualidade do cuidado em Instituições de Longa Permanência para Idosos (ILPI), denominado QualificaILPI. Método Estudo metodológico realizado entre março e dezembro de 2021. O instrumento foi desenvolvido com base em modelo multidimensional de qualidade, legislação brasileira e pesquisa bibliográfica e contém padrões de qualidade para autoavaliação das ILPI nas dimensões: ambiente, lar, cuidado, envolvimento familiar e da comunidade, equipe de trabalho e gestão. Cada padrão é descrito e seguido por uma escala, com parâmetros para classificar o nível de qualidade da ILPI em incipiente, intermediário, consolidado. A Técnica Delphi modificada foi empregada para validação por um comitê de 10 especialistas quanto a pertinência do padrão para avaliação da qualidade da ILPI, da adequação dos objetivos e da escala de avaliação, clareza, podendo fazer comentários. O padrão foi mantido quando houve 75% de concordância entre os especialistas. O instrumento foi também avaliado pelo público-alvo, constituído por coordenadores de 10 ILPI, selecionadas por conveniência. Resultados No primeiro ciclo de avaliação, foram excluídos três padrões e dois novos foram criados. No segundo, alterou-se a dimensão de um padrão e dois padrões foram unidos. Ao final, permaneceram 29 padrões divididos em seis dimensões. O público-alvo, gestores de ILPI, sugeriu alterações na redação de alguns padrões. Houve consenso de 80% ou superior em todos os padrões. Conclusão O QualificaILPI poderá contribuir para o monitoramento das ILPI favorecendo a melhoria do cuidado ofertado aos residentes.

Abstract Objective To develop and validate the content of a self-assessment instrument for the quality of care in Long-Term Care Facilities for Older Adults (Instituições de Longa Permanência para Idosos - ILPIs), named QualificaILPI. Method A methodological study conducted between March and December 2021. The instrument was developed based on a multidimensional quality model, Brazilian legislation, and literature research. It contains quality standards for self-assessment of ILPIs in the dimensions of environment, home, care, family and community involvement, work team, and management. Each standard is described and followed by a scale with parameters to classify the level of ILPI quality as incipient, intermediate, or consolidated. The modified Delphi Technique was employed for validation by a committee of 10 experts regarding the relevance of the standard for ILPI quality assessment, the appropriateness of objectives, the evaluation scale, and clarity, allowing for comments. The standard was retained when there was 75% agreement among the experts. The instrument was also evaluated by the target audience, consisting of coordinators from 10 ILPIs selected for convenience. Results In the first assessment cycle, three standards were excluded, and two new ones were created. In the second cycle, the dimension of one standard was changed, and two standards were combined. In the end, 29 standards remained, divided into six dimensions. The target audience, ILPI managers, suggested changes in the wording of some standards. There was a consensus of 80% or higher for all standards. Conclusion QualificaILPI has the potential to contribute to monitoring ILPIs, promoting the improvement of care offered to residents.

Avaliação das Instituições de Longa Permanência para Idosos no Brasil: um panorama das desigualdades regionais / Evaluation of Long-Term Institutions for Older People in Brazil: an overview of regional inequalities

Resumo O objetivo deste artigo é avaliar as Instituições de Longa Permanência para Idosos (ILPI) brasileiras, segundo o Modelo Teórico Multidimensional Integrado de Qualidade e Atendimento (MIQA), e comparar o desempenho alcançado entre as regiões do país. Estudo ecológico descritivo realizado com dados secundários públicos das ILPI participantes do Censo do Sistema Único da Assistência Social de 2018. Uma Matriz de Avaliação foi construída a partir das variáveis do Censo e do Modelo Teórico MIQA. Parâmetros de qualidade foram empregados para classificar o desempenho das instituições para cada indicador em "incipiente", "em desenvolvimento" ou "desejável. O índice de disparidade foi obtido para cada indicador. Foram analisadas 1.665 instituições. Observaram-se diferenças nos percentuais de ILPI com desempenho "desejável" entre as regiões brasileiras, e a necessidade de aprimoramento na maioria das ILPI em relação à proporção de cuidadores de pessoas idosas, a composição da equipe multiprofissional, a acessibilidade e a oferta de ações de promoção de saúde. Verificou-se a necessidade de apoio governamental para a supressão dos critérios de diferenciações excludentes e para a expansão dos serviços para superar as superlotações.

Abstract This article aims to evaluate the Brazilian Long-Term Institutions for Older People (LTIE), according to the Integrated Multidimensional Theoretical Model of Quality and Service (MIQA), and compare the performance achieved between the regions of the country. Descriptive ecological study carried out with public secondary data from the LTIE participating in the 2018 Census of the Unified Social Assistance System. An Evaluation Matrix was constructed from the Census variables and the MIQA Theoretical Model. Quality parameters were used to classify the institutions' performance for each indicator as "incipient", "developing" or "desirable". The disparity index was obtained for each indicator. 1,665 institutions were analyzed. Differences were observed in the percentages of LTIE with "desirable" performance between Brazilian regions, and the need for improvement in most LTIE in relation to the proportion of caregivers of older people, the composition of the multidisciplinary team, accessibility and supply of health promotion actions. There was a need for government support for the suppression of exclusionary differentiation criteria and for the expansion of services to overcome overcrowding.

Integração das ações do Programa Saúde na Escola entre profissionais da saúde e da educação: um estudo de caso em Belo Horizonte, Minas Gerais / Integration of School Health Program actions among health and education professionals: a case study in Belo Horizonte, Minas Gerais

RESUMO O Programa Saúde na Escola tem como meta a construção de escolas saudáveis. Estudo de caso, de abordagem qualitativa com intenção de identificar e compreender como se comportam, no esforço de integração, profissionais envolvidos no Programa Saúde na Escola, a partir de sua inserção nas atividades preconizadas. Após construção do modelo lógico do programa, foi realizado consenso com experts para elaboração de matriz de indicadores, originando roteiro semiestruturado. Foram realizadas 25 entrevistas, nas Unidades Básicas de Saúde e Escolas de Ensino Fundamental, além das Gerências Regionais da Saúde e da Educação. As práticas foram consideradas multissetoriais, sem soma de esforços e coparticipação efetiva, sendo planejadas por um único setor ou profissional; os gaps existentes são reconhecidos tanto quanto a importância do programa; as práticas acontecem com baixo vínculo entre equipes. A forma fragmentada de perceber os problemas dos escolares dificulta essa integração.

ABSTRACT The School Health Program aims to build healthy schools. This qualitative case study aimed to identify and understand how professionals involved in the School Health Program behave in the integration based on their inclusion in the recommended activities. The consensus was reached with experts to develop a matrix of indicators after building the Program's logical model, resulting in a semi-structured roadmap. Twenty-five interviews were held in the Basic Health Units, Elementary Schools, and the Regional Health and Education Administrations. The practices were multisectoral, with no combined efforts and effective co-participation, planned by a single sector or professional, the existing gaps are recognized as much as the importance of the program, and the practices are implemented with a low bond between teams. The fragmented perception of students' problems hinders this integration.

El anillo vaginal de progesterona como soporte de la fase lútea en fertilización in vitro

Objetivo. Comparar la efectividad del anillo vaginal y las cápsulas vaginales de progesterona en el soporte de la fase lútea en procedimientos de fertilización in vitro. Métodos. Estudio retrospectivo que evaluó los resultados de embarazo en mujeres receptoras de embriones logrados de donación de ambos gametos al comparar la efectividad del anillo vaginal y las cápsulas vaginales de progesterona en el soporte de la fase lútea en procedimientos de fertilización in vitro. Resultados. 38 mujeres usaron el anillo vaginal y 46 aplicaron las cápsulas vaginales como soporte de la fase lútea. Se halló tasas similares de implantación (36,5% versus 36,9%), embarazo clínico (52,6% versus 50,0%) y nacido vivo (50,0% versus 45,7%). Conclusiones. Se halló tasas similares de implantación, embarazo clínico y nacido vivo con el empleo del anillo vaginal y las cápsulas vaginales de progesterona en el soporte de la fase lútea en procedimientos de fertilización in vitro. Debido a la comodidad de su uso y a las adecuadas tasas de embarazo, el anillo vaginal de progesterona se constituye como una alternativa importante en el soporte de la fase lútea en la fertilización in vitro.

Objective: To compare the effectiveness of the vaginal ring and vaginal progesterone capsules in supporting the luteal phase in in vitro fertilization procedures. Methods: Retrospective study that evaluated pregnancy outcomes in female recipients of embryos obtained from donation of both gametes by comparing the effectiveness of the vaginal ring and vaginal progesterone capsules in supporting the luteal phase in in vitro fertilization procedures. Results: Thirty-eight women used the vaginal ring and 46 applied vaginal capsules as luteal phase support. Similar rates of implantation (36.5% versus 36.9%), clinical pregnancy (52.6% versus 50.0%) and live birth (50.0% versus 45.7%) were found. Conclusions: Similar implantation, clinical pregnancy and live birth rates were found with the use of the vaginal ring and vaginal progesterone capsules in the support of the luteal phase in in vitro fertilization procedures. Due to the convenience of its use and adequate pregnancy rates, the progesterone vaginal ring is an important alternative in the support of the luteal phase in in vitro fertilization.

Percepção e atitude do cirurgião-dentista diante do atendimento emergencial a mulheres em situação de violência: uma revisão de escopo / Dentists' perceptions and attitudes towards emergency care for women in situations of violence: a scope review

Resumo Avaliar por meio de uma revisão de escopo estudos que abordam a percepção e atitude do cirurgião-dentista diante do atendimento a mulheres em situação de violência. Utilizando os descritores women violence, dentist attendence ou dentist care, foram identificados 473 artigos, sendo incluídos 13, ao final da seleção. Embora a necessidade de capacitação tenha sido predominante, ela não é suficiente. Existe uma fragilidade em se compreender a violência como problema de saúde, de entender o papel do profissional na solução desse problema, os fatores que podem contribuir com seu crescimento ou seu controle. Os resultados revelaram que o cirurgião-dentista apresentou maior dificuldade do que os outros profissionais no enfrentamento e exigem um amplo aprendizado. O reconhecimento dos referidos casos pelo cirurgião-dentista exige a incorporação de medidas educativas que provoquem mudanças culturais, desconstrução de normas de gênero e a desnaturalização desse fenômeno social.

Abstract The purpose of this study was to evaluate, through a scope review, studies that address the perceptions and attitudes of dentists regarding the care of women in situations of violence. Using the descriptors women violence, dentist attendance or dentist care, 473 articles were identified, of which 13 were included at the end of the selection process. Although the need for training was predominant, it was not sufficient. There is a weakness in understanding violence as a health problem, in understanding the role of the professional in solving this problem, and the factors that can contribute to its growth or its control. The results revealed that the dentist had greater difficulty than other professionals in coping with the issue and required extensive training. The recognition of these cases of abuse by the dentist requires the incorporation of educational measures that cause cultural changes, deconstruction of gender norms and the denaturalization of this social phenomenon.

Exposure to common-use pesticides, manganese, lead, and thyroid function among pregnant women from the Infants' Environmental Health (ISA) study, Costa Rica.

BACKGROUND: Pesticides and metals may disrupt thyroid function, which is key to fetal brain development. OBJECTIVES: To evaluate if current-use pesticide exposures, lead and excess manganese alter free thyroxine (FT4), free triiodothyronine (FT3), and thyroid stimulating hormone (TSH) concentrations in pregnant women from the Infants' Environmental Health Study (ISA). METHODS: At enrollment, we determined women's (n = 400) specific-gravity corrected urinary pesticide (µg/L) metabolite concentrations of mancozeb (ethylene thiourea (ETU)), pyrimethanil, thiabendazole, chlorpyrifos, synthetic pyrethroids, and 2,4-D. We also measured manganese hair (MnH) (µg/g) and blood (MnB) (µg/L), and blood lead (PbB) (µg/L) concentrations. To detect an immediate and late effect on thyroid homeostasis, we determined TSH, FT4 and FT3 in serum obtained at the same visit (n = 400), and about ten weeks afterwards (n = 245). We assessed associations between exposures and outcomes with linear regression and general additive models, Bayesian multivariate linear regression, and Bayesian kernel machine regression. RESULTS: About 80%, 94%, and 100% of the women had TSH, FT4, and FT3 within clinical reference ranges, respectively. Women with higher urinary ETU, and pyrimethanil-metabolites, had lower FT4: ß = -0.79 (95%CI = -1.51, -0.08) and ß = -0.29 (95%CI = -0.62, -0.03), respectively, for each tenfold increase in exposure. MnB was positively associated with FT4 (ß = 0.04 (95%CI = 0.00, 0.07 per 1 µg/L increase), and women with high urinary pyrethroid-metabolite concentrations had decreased TSH (non-linear effects). For the late-effect analysis, metabolites of pyrethroids and chlorpyrifos, as well as MnH, and PbB were associated decreased TSH, or increased FT4 and/or FT3. DISCUSSION: Mancozeb (ETU) and pyrimethanil may inhibit FT4 secretion (hypothyroidism-like effect), while chlorpyrifos, pyrethroids, MnB, MnH, PbB and Mn showed hyperthyroidism-like effects. Some effects on thyroid homeostasis seemed to be immediate (mancozeb (ETU), pyrimethanil, MnB), others delayed (chlorpyrifos, MnH, PbB), or both (pyrethroids), possibly reflecting different mechanisms of action.

Papel pronóstico de factores asociados con lesión isquémica de la circulación anterior: estudio de cohorte / Prognosis role of factors associated with anterior circulation stroke: a cohort study

RESUMEN INTRODUCCIÓN: La enfermedad cerebrovascular constituye un problema de salud pública. Esta entidad representa una importante causa de discapacidad permanente en el adulto, además de tener impacto social, económico y sanitario. Los altos costos que demanda la atención sanitaria desde su momento diagnóstico, el manejo inicial del evento y la posterior rehabilitación-paliación de las secuelas, obligan al conocimiento de características del individuo y factores pronósticos. Esto como insumo de planificación de servicios de prevención para personas en riesgo y atención de pacientes con ataque cerebrovascular. OBJETIVO: Identificar el papel pronóstico que tienen algunos factores asociados con la lesión isquémica, con respecto al grado de discapacidad y mortalidad en el infarto cerebral de la circulación anterior. METODOLOGÍA: Estudio observacional analítico, prospectivo de cohorte, con un análisis anidado de casos y controles. Se identificó la escala del National Institute of Health Stroke Scale (NIHSS) para determinar el compromiso neurológico al ingreso. A los tres meses del evento, se obtuvo la escala Rankin modificado (mRS, variable dependiente) en busca de discapacidad residual y mortalidad; se consideraron casos los mRS desfavorables (puntajes: 3, 4, 5 y 6), y controles los mRS favorables (puntajes: 0, 1, 2). RESULTADOS: Se incluyeron 93 pacientes con ACV-i de circulación anterior; la mediana para la edad fue 67 años RIC (57-76); el NIHSS más frecuente fue moderado (50 pacientes, 53,8 %) y la mediana de tiempo transcurrido para el inicio de manejo médico fue de 5 horas RIC (3-24 horas). La identificación de la etiología del ACVi fue posible en 33 pacientes (35,5 %, más frecuente el cardioembólico). Luego de 90 días del ACVi, la clasificación mRS más frecuente fue de tres puntos "moderado" (22 pacientes, 23,7 %) y la mortalidad fue de siete pacientes (7,5 %). En el análisis bivariado la ubicación del infarto en el hemisferio izquierdo fue una variable desfavorable en términos de discapacidad a los tres meses en comparación con el hemisferio derecho (OR: 2,51; IC 95 %: 1,06 - 5,9; p = 0,03). CONCLUSIONES: La población de estudio fue predominantemente de sexo masculino, con una limitación funcional moderada (NIHSS 5-15) al ingreso a urgencias. Tres meses después del evento, la mayoría de los pacientes cursó con movilidad reducida, algún compromiso de las funciones mentales, pero esencialmente independientes en su vida diaria. La lesión del hemisferio izquierdo se comportó como un factor de mal pronóstico en la recuperación funcional de los pacientes.

SUMMARY INTRODUCTION: Cerebrovascular disease constitutes a public health problem. This entity represents an important cause of permanent disability in adults, social, economic and health impact as well. The high costs demanded by health care from the moment of diagnosis, initial management of the event, and subsequent rehabilitation-palliation of the sequelae, requires knowledge of population characteristics and possible prognostic factors. This can be useful as an input for planning prevention services for people at risk and care of stroke patients. OBJECTIVE: To identify the prognostic role that some factors associated with the ischemic lesion have regarding the degree of disability and mortality, in the cerebral infarction of the anterior circulation. Methods: Observational, analytical, prospective cohort study was performed, with a nested case-control analysis. Neurological involvement was measured at admission with the NIHSS scale. At three months post-event, the modified Rankin scale (mRS: dependent variable) was measured, pursuing residual disability and mortality; cases: patient with unfavorable mRS score (score: 3, 4, 5, 6); controls: patient with favorable mRS score (score: 0, 1, 2). RESULTS: 93 patients with diagnosis of ischemic stroke of anterior circulation were included. Median age was 67 years RIQ (57-76); most frequent NIHSS was moderate (50; 53.8 %) and the median evolution time to medical management was 5 hours RIQ (3-24 hours). Etiology was identified in 33 patients (35.5 %, cardio-embolic the most). After 90 days since ischemic injury, most frequent mRS was "3: moderate" (22; 23.7 %) and 7 (7.5 %) patients died. Bivariate analysis identified left hemisphere stroke as an unfavorable variable in terms of disability at three months compared to the right hemisphere (OR 2.51, 95 % CI 1.06-5.9, p = 0.03). CONCLUSIONS: The population with ischemic stroke was predominantly males with multiple comorbidities, with a moderate neurological compromise on admission (NIHSS score: 5-15). After three months post event, patients were predominantly with reduced mobility, some mental functions affection, but essentially independent in activities of daily living. The involvement of left hemisphere is projected as poor prognostic factor in the functional recovery of our patients.

Open Fetal Microneurosurgery for Intrauterine Spina Bifida Repair.

OBJECTIVES: The aim of the study was to describe the feasibility of open fetal microneurosurgery for intrauterine spina bifida (SB) repair and to compare perinatal outcomes with cases managed using the classic open fetal surgery technique. METHODS: In this study, we selected a cohort of consecutive fetuses with isolated open SB referred to our fetal surgery center in Queretaro, Mexico, during a 3.5-year period (2016-2020). SB repair was performed by either classic open surgery (6- to 8-cm hysterotomy with leakage of amniotic fluid, which was replaced before uterine closure) or open microneurosurgery, which is a novel technique characterized by a 15- to 20-mm hysterotomy diameter, reduced fetal manipulation by fixing the fetal back, and maintenance of normal amniotic fluid and uterine volume during the whole surgery. Perinatal outcomes of cases operated with the classic open fetal surgery technique and open microneurosurgery were compared. RESULTS: Intrauterine SB repair with a complete 3-layer correction was successfully performed in 60 cases either by classic open fetal surgery (n = 13) or open microneurosurgery (n = 47). No significant differences were observed in gestational age (GA) at fetal intervention (25.4 vs. 25.1 weeks, p = 0.38) or surgical times (107 vs. 120 min, p = 0.15) between both groups. The group with open microneurosurgery showed a significantly lower rate of oligohydramnios (0 vs. 15.4%, p = 0.01), preterm rupture of the membranes (19.0 vs. 53.8%, p = 0.01), higher GA at birth (35.1 vs. 32.7 weeks, p = 0.03), lower rate of preterm delivery <34 weeks (21.4 vs. 61.5%, p = 0.01), and lower rate of perinatal death (4.8 vs. 23.1%, p = 0.04) than the group with classic open surgery. During infant follow-up, the rate of hydrocephalus requiring ventriculoperitoneal shunting was similar between both groups (7.5 vs. 20%, p = 0.24). All patients showed an intact hysterotomy site at delivery. CONCLUSION: Intrauterine spina repair by open fetal microneurosurgery is feasible and was associated with better perinatal outcomes than classic open fetal surgery.

Cytotoxic Effects of Blue Scorpion Venom (Rhopalurus junceus) in a Glioblastoma Cell Line Model.

BACKGROUND: Cancer is one of the leading cause of death worldwide. Besides current therapies and treatments to counter cancer, new alternatives are required to diminish the cell proliferation of oncogenic processes. METHODS: One of the most promissory therapy includes the use of blue scorpion venom as a specific cytotoxic agent to kill tumoral cells, including Glioblastoma multiforme. OBJECTIVES: We show evidence of the cytotoxic effect of blue scorpion venom in a cellular model of Glioblastoma multiforme. RESULTS: Our results demonstrate that 50 µg/ml of scorpion venom is capable to diminish the viability of Glioblastoma populations. CONCLUSION: It is possible that the action mechanism could be associated with a loss of membrane integrity. Additionally, some metalloproteinases as MMP2 and MMP9 may also participate in the potential action mechanism.

Análise de detecção automática de interação qui-quadrado (chaid) das diferenças de gênero determinantes de sintomas depressivos em idosos / Chi-square automatic interaction detection (chaid) analysis of sex differences determining of depressive symptoms in the elderly

O objetivo deste estudo foi determinar a prevalência de sintomas depressivos em idosos residentes em comunidade e analisar a associação entre depressão, condições socioeconômicas e de saúde estratificadas por sexo. A presente investigação deriva de análise da linha de base do estudo Aging, Gender and Quality of Life (AGEQOL), é uma coorte envolvendo 2.052 indivíduos com 60 anos de idade ou mais, residentes na comunidade em um município brasileiro. Os sintomas de depressão foram avaliados pela escala de 15 itens de Depressão Geriátrica. A Regressão de Poisson foi utilizada para avaliar associações com covariáveis. Análise de Árvore de Decisão foi utilizada para investigar fatores preditores de sintomas depressivos separadamente entre homens e mulheres. A prevalência de sintomas depressivos na população estudada foi de 30,2% (34,4% entre as mulheres e 23,8% entre os homens). Para o sexo masculino, os sintomas depressivos foram explicados por faixa etária (p=0,025), doenças crônicas (p=<0,001), capacidade funcional para AIVD (p=0,005) e arranjos domiciliares (p=0,002). Para o sexo feminino, o padrão de preditores de sintomas depressivos foi significativamente diferente entre os grupos etários (p=0,005). Conclui-se que existem diferenças relevantes entre os sexos na prevalência de sintomas depressivos observados em idosos, que podem ser explicadas por idade, capacidade funcional, doenças crônicas e arranjos domiciliares.(AU)

Our objective was to determine the prevalence of depressive symptoms in community-dwelling elderly and to analyze the association between depression, socioeconomic and health conditions stratified by sex. This research comes from the baseline analysis of the AGEQOL study (Aging, Gender, and Quality of Life) is a cohort study involving 2052 individuals aged 60 years or older, living in the community in a Brazilian town. Depression symptoms were assessed using was assessed using the scale of 15 items Geriatric Depression. We used Poisson regression to assess associations with covariates, and analysis of the decision to investigate predictors of depressive symptoms among men and women separately. The prevalence of depressive symptoms in this population was 30.2% (34.4% among women and 23.8% among men). For males, depressive symptoms were explained by age (p=0.025), chronic diseases (p<0.001), functional capacity for IADL (p=0.005) and living arrangements (p=0.002). For females, the pattern of predictors of depressive symptoms was significantly different between the groups (p=0.005). We conclude that there are significant differences between genders in the prevalence of depressive symptoms in the elderly, which could be explained by age, functional ability, chronic illness, and living arrangements.(AU)

A ciência da saúde coletiva por escrito: contribuição para estudos em saúde bucal coletiva / The science of collective health in writing: contribution to studies in collective oral health

Resumo Comemorando os 25 anos da Revista Ciência & Saúde Coletiva (C&SC), o presente artigo analisou 375 documentos publicados entre 2000-2019 neste periódico, como parte integrante da editoria de saúde bucal coletiva. A análise da produção visou compreender como o núcleo de saúde bucal aparece nas publicações e como poderia ter contribuído com o conhecimento sobre a saúde-doença da população, as políticas públicas específicas, o ensino e a gestão dos serviços de saúde bucal no SUS. O processo privilegiou a análise bibliométrica e a de documentos. Foi possível explicitar a distribuição institucional dos autores, sua expressiva rede de colaboradores e a dimensão das citações das publicações inclusive no plano internacional. Os estados brasileiros mais presentes nas publicações foram São Paulo e Minas Gerais, seguidos por autores de Pernambuco, Rio Grande do Sul e Santa Catarina. As citações foram mais frequentemente do Brasil (85,14%), seguido por Estados Unidos (2,31%), Portugal (1,34%) e Austrália (1,34%). Conclui-se que, mesmo com limitações, C&SC se mostrou, inequivocamente, um potente instrumento de divulgação da produção científica na perspectiva da saúde bucal coletiva, possibilitando a divulgação e o intercâmbio de informações, facilitando a integração entre os pesquisadores e possibilitando um caminho da sua consolidação.

Abstract Celebrating the 25 years of existence of the Journal Ciência & Saúde Coletiva (C&SC), this paper analyzed 375 documents published between 2000-2019 as an integral part of the editorial of collective oral health. The production analysis aimed to understand how oral health core appears in publications and how it could have contributed to knowledge on the population's health-disease, specific public policies, education, and management of oral health services in the SUS. The process employed bibliometric and documental analysis. We could show the authors' territorial distribution, their extensive collaboration network, and the dimension of citations in publications, including the international plan. The Brazilian states most present in the publications were São Paulo and Minas Gerais, followed by authors from Pernambuco, Rio Grande do Sul, and Santa Catarina. Citations were more frequent in Brazil (85.14%), followed by the United States (2.31%), Portugal (1.34%), and Australia (1.34%). We concluded that, despite the limitations, the C&SC showed unequivocally a powerful instrument for the dissemination of scientific production from the perspective of collective oral health, enabling the exchange of information and facilitating the integration between researchers and enabling a path to its consolidation.

Twins from different fathers: A heteropaternal superfecundation case report in Colombia / Gemelos de diferentes padres: un caso de superfecundación heteropaternal en Colombia

Abstract: Heteropaternal superfecundation is an extremely rare phenomenon that occurs when a second ova released during the same menstrual cycle is additionally fertilized by the sperm cells of a different man in separate sexual intercourse. In August, 2018, the Grupo de Genética de Poblaciones e Identificación at Universidad Nacional de Colombia received a request to establish the paternity of a pair of male twins with genetic markers. The following analyses were performed: amelogenin gene, autosomal short tandem repeat (STR), and Y-STR analyses by means of human identification commercial kits, paternity index, and the probability of paternity calculation and interpretation. A paternity index of 2.5134E+7 and a probability of paternity of 99.9999% for twin 2 were obtained while 14 out of 17 Y-chromosome markers and 14 out of 21 autosomal short tandem repeats were excluded for twin 1. The results indicated that the twins have different biological fathers. Although heteropaternal superfecundation is rarely observed among humans given its low frequency, in paternity disputes for dizygotic twins it is mandatory to demand the presence of the two twins in the testing to avoid wrong conclusions.

Resumen: La superfecundación heteropaternal es un fenómeno extremadamente raro que se produce cuando un segundo óvulo, liberado durante el mismo ciclo menstrual, es fertilizado por un espermatozoide de un hombre diferente en relaciones sexuales separadas. En agosto de 2018, el Grupo de Genética de Poblaciones e Identificación de la Universidad Nacional de Colombia recibió una solicitud para establecer la paternidad mediante marcadores genéticos de un par de mellizos varones, en quienes se hizo el análisis del gen de amelogenina, el análisis de repeticiones cortas en tándem (Short Tandem Repeats, STR) autosómicas y del cromosoma Y (Y-STR) mediante kits comerciales de identificación humana y cálculos e interpretación del índice de paternidad y probabilidad de paternidad. Se obtuvo un índice de paternidad de 2,5134E+7 y una probabilidad de paternidad de 99,9999 % para el gemelo 2, en tanto que en el gemelo 1 se excluyeron 14 de los 17 marcadores del cromosoma Y y 14 de los 21 sistemas STR autosómicos evaluados. Los resultados indicaron que los gemelos tienen diferentes padres biológicos. A pesar de que la superfecundación heteropaternal rara vez se observa en humanos debido a su baja frecuencia, en las disputas de paternidad para los gemelos dicigóticos, es obligatorio exigir en la prueba la presencia de los dos gemelos para evitar conclusiones incorrectas.

Embarazo heterotópico: reporte de un caso / Heterotopic pregnancy: a case report

Se presenta el caso clínico de una paciente de sexo femenino de 36 años de edad, natural de Cochabamba, con embarazo ectópico tubárico en la trompa derecha, asociado a un embarazo intrauterino de 6.4 semanas de gestación por FUM, sin antecedentes patológicos personales ni familiares de relevancia clínica; fue tratada quirúrgicamente en el Hospital Obrero Nro 2 CNS, optándose por la laparotomía con salpinguectomía; se realizó prevención de aborto del saco intrauterino con resultados satisfactorios.

The case of a female patient 36 years old, born in Cochabamba, with tubal ectopic pregnancy in the fallopian right, associated with an intrauterine pregnancy of 6.4 weeks LMP, with no personal or family history of disease clinical relevance is presented; He was treated surgically in the CNS Hospital Obrero No. 2, whichever laparotomy with salpingectomy and prevention of intrauterine sac abortion was performed with satisfactory results.

Indicadores para avaliação das instituições de longa permanência para pessoas idosas: desenvolvimento e validação / Indicators for evaluating long-term care facilities for old people: development and validation

Resumo Objetivo Desenvolver e validar uma matriz de avaliação da qualidade de Instituições de Longa Permanência para pessoas idosas, tendo como referencial teórico o modelo multidimensional integrado de qualidade e atendimento. Método Trata-se de um estudo metodológico que selecionou 66 variáveis contempladas no censo do Sistema Único da Assistência Social, para avaliar as sete dimensões de qualidade propostas pelo modelo. A técnica Delphi modificada foi empregada para a validação com a participação de 15 experts que utilizaram a plataforma on-line Survey Monkey®, até a obtenção de, no mínimo, 75% de consenso. Foram propostos 18 indicadores e necessários dois ciclos de validação até o consenso. Resultados No primeiro ciclo, todos os indicadores foram considerados relevantes, representaram o conceito e demonstraram coerência com a dimensão teórica da qualidade. Houve necessidade de revisão da fórmula de cálculo de dois indicadores, que foi considerada adequada por mais de 75% dos experts no segundo ciclo de validação. Conclusão A matriz mostrou-se válida e poderá ser utilizada no processo de avaliação e monitoramento da qualidade das Instituições participantes do Censo do Sistema Único de Assistência Social, contribuindo para definir prioridades para a permanente melhoria dos cuidados prestados.

Abstract Objective Develop and validate a quality assessment matrix for long-term facilities for old people, using the integrated multidimensional model of quality and care as the theoretical framework. Method This is a methodological study that selected 66 variables included in the census of the Unified System of Social Assistance, to assess the seven dimensions of quality proposed by the model. The modified Delphi technique was used for validation with the participation of 15 experts who used the Survey Monkey® online platform, until a minimum of 75% consensus was reached. 18 indicators were proposed and two validation cycles were needed until consensus. Results In the first cycle, all indicators were considered relevant, represented the concept and demonstrated consistency with the theoretical dimension of quality. There was a need to review the calculation formula for two indicators, which was considered adequate by more than 75% of experts in the second validation cycle. Conclusion The matrix proved to be valid and can be used in the process of evaluating and monitoring the quality of the facilities participating in the Unified Social Assistance System Census, contributing to define priorities for the permanent improvement of the care provided.

Paciente masculino con cariotipo 46 XX negativo para el gen SRY y sin ambigüedad genital: reporte de un caso / Male patient 46, XX SRY -negative and unambiguous genitalia: A case report

En la mayoría de los casos, la diferenciación sexual masculina ocurre con la participación del gen SRY. Sin embargo, se pueden presentar otros genotipos excepcionales, como en el caso que se presenta en este reporte. Se trata de un paciente adulto de sexo masculino atendido en el Servicio de Paternidades del Instituto de Genética de la Universidad Nacional de Colombia. Se le hicieron los análisis del gen de la amelogenina y de repeticiones cortas en tándem (Short Tandem Repeat, STR) específicas para el gen SRY con estuches comerciales de identificación humana, así como los de cariotipo convencional e hibridación in situ fluorescente del SRY, y el estudio de microdeleciones del cromosoma Y mediante reacción en cadena de la polimerasa (PCR). Se le hizo la evaluación clínica y se le brindó asesoramiento genético. El paciente no presentaba ambigüedad genital, su cariotipo era 46 XX, y el perfil molecular era negativo para el gen SRY y positivo para el ZFY. Se le diagnosticó un trastorno de diferenciación sexual 46 XX testicular no sindrómico, una rara condición genética. Solo el 20 % de los pacientes con este diagnóstico son negativos para SRY y exhiben perfiles moleculares diversos. La información disponible parece indicar que el ZFY está relacionado con la diferenciación sexual masculina, aún en ausencia del gen SRY.

In most cases, male sexual differentiation occurs with SRY gene mediation. However, exceptional genotypes have been identified, as shown in this paper. This was a male adult patient seen at the Servicio de Paternidades, Instituto de Genética, Universidad Nacional de Colombia. The following procedures were carried out: Amelogenin gene and short tandem repeat analyses using human identification commercial kits, conventional karyotype, SRY fluorescent in situ hybridization, PCR analysis for Y chromosome microdeletions, clinical evaluation, and genetic counseling. We present an adult male with unambiguous genitalia, karyotype 46,XX, and an SRY negative and ZFY positive molecular profile. The diagnosis of nonsyndromic 46,XX testicular disorder of sex development (DSD) -a rare genetic condition- was established. Only 20 % of similarly diagnosed patients are SRY negative and exhibit diverse molecular profiles. Until now, available evidence seems to indicate that, even in the absence of SRY, the ZFY factor is involved in male sexual differentiation.

Perfil clínico-funcional de niños que ingresan a un programa de rehabilitación oncológica en una ONG chilena / Clinical-functional profile of children admitted into an oncology rehabilitation program in a Chilean NGO

INTRODUCCIÓN: Los pacientes oncológicos infantiles presentan diversas deficiencias en sus funciones y estructuras corporales derivados de los tumores mismos o de los distintos tratamientos empleados, ya sea cirugía, quimioterapia, radioterapia o la suma de ellos. Estas deficiencias generan gran discapacidad en todas las áreas del funcionamiento. OBJETIVO: Describir el perfil clínico y funcional de niños que ingresan a un programa de rehabilitación oncológica. MATERIALES Y MÉTODOS: Estudio observacional, restrospectivo y descriptivo. Se revisaron 109 fichas clínicas de pacientes ingresados al programa de rehabilitación oncológica de Fundación Nuestros Hijos entre los años 2014 y 2017, que cumplieron criterios de ingreso. Se obtuvieron los datos de la evaluación clínica realizada por médico fisiatra y pruebas funcionales al ingreso, incluyendo Timed Up and Go Test, Pediatric Balance Scale y test de Marcha de 6 min. RESULTADOS: El promedio de edad fue de 8,7 ± 3,4 años. Los diagnósticos más frecuentes fueron tumores de sistema nervioso central (50,4%), leucemias y linfomas (24,4%). Un 53,2% de los pacientes se encontraba en tratamiento activo al momento del ingreso. El déficit motor fue el más frecuente (79,8%). Dentro de este grupo, 19 niños (17,4%) presentaron hemiparesia y 18 niños (16,5%) tetraparesia. Del total, 44% reportó presencia de fatiga, 28,4% presentó trastorno de la deglución, 34,9% trastorno visual y un 56,9% compromiso cognitivo.CONCLUSIONES: Los niños que ingresan a rehabilitación oncológica presentan múltiples deficiencias en diversas áreas de su funcionamiento, tanto en etapas tempranas como tardías de su tratamiento. El compromiso, motor, deglutorio, visual y cognitivo son las deficiencias más frecuentes de encontrar, sobre todo en pacientes con tumores de SNC.

INTRODUCTION: Pediatric cancer patients present several dysfunctions in their body functions and structures caused by the tumors or by therapies, such as surgery, chemotherapy, radiotherapy or the sum of all of these treatments. these dysfunctions cause impairment of all areas of functioning. OBJECTIVE: to describe the clinical and functional profile of children admitted to an oncology rehabilitation program. MATERIALS AND METHODS: A retrospective, descriptive, observational study that reviewed 109 clinical records of patients admitted between 2014 and 2017 to the oncology rehabilitation program of 'Fundación Nuestros Hijos', in compliance with the admission criteria. Data were obtained from the clinical assessment performed by the physiatrist and from functional tests such as 'Timed Up and Go Test', 'Pediatric Balance Scale' and '6-minute walk test'. RESULTS: Average age was 8.7 ± 3.4 years. the most frequent diagnoses were central nervous system (CNS) tumors (50.4%), leukemia and lymphoma (24.4%). A 53.2% of the patients were under active treatment at the time of admission. Motor deficit was the most frequent symptom (79.8%). In this group, 19 children (17.4%) had hemiparesis and 18 (16.5%) quadraparesis. of the total, 44% reported fatigue, 28.4% swallowing disorders, 34.9% vision disorders, and 56% cognitive impairment. CONCLUSIONS: Children admitted to oncology rehabilitation programs present several deficiencies in areas of functioning, both in early and late stages of their treatment. Motor, visual and swallowing impairment are the most common dysfunctions, particularly in patients with CNS tumors.

"Tihik quando bebe Kaxmuk não tem pai, nem mãe, nem irmão": Percepções sociais das consequências do uso da cachaça no povo indígena Maxakali/MG/Brasil / "When a Tihik drinks kaxmuk he neither has a father, nor a mother, or a brother": perceptions of Maxakali on the effects of sugarcane liquor consumption

Resumo Este artigo explora um dos aspectos mais interessantes e menos estudados no Brasil: as consequências das experiências complexas e contraditórias da substituição total de bebidas tradicionais indígenas pela cachaça, introduzida pelo contato interétnico. Contribui com a carência de ampliação de estudos na temática, analisando as consequências negativas do uso de álcool Maxakali. Enquanto estudos antropológicos enfatizam funções do beber tradicional e contemporâneo como "lubrificantes" sociais, as percepções sociais Maxakali ressaltam consequências negativas do uso da cachaça vendida ou trocada no contato interétnico. Interpretou-se no cotidiano, símbolos e significados dessas consequências, narradas por 21 lideranças em grupos focais. Com a substituição da Kaxmuk pelos Maxakali, ocorreram adaptações surgidas pelo contato interétnico, com relações negativas para quem bebe, suas família, aldeia e comunidade. No mundo-da-vida, as consequências negativas apresentaram-se em forma de acidentes, desarmonias conjugais, negligências, além de comportamentos violentos, doenças e mortes. Este estudo reforça a importância de produção de conhecimentos aprofundados e abrangentes visando a identificação de grupos vulneráveis em busca de soluções participantes.

Abstract This study explores one of the most interesting and least studied issues in Brazil: the consequences of complex and contradictory experiences by replacing the traditional drinks by cachaça, introduced through interethnic contact. Given the rarity of the study of Maxakali alcohol consumption in research, this study aims to understand, from the native's point of view, the negative aftereffect of alcohol consumption. Although anthropological studies emphasize functions of traditional and contemporary drinking as social "lubricants", social perceptions of the Maxakali highlight the problems of cachaça bought through interethnic contact. Symbols and meanings of these consequences were interpreted through their daily life histories, recorded by 21 leaders in focus group. Through the interethnic contact, some adaptations have occurred in the Maxakali alcohol use, with negative consequences for those who drink, their families, their villages and their community. In the world-of-life, these changes these changes can be seen through accidents, insults, marital disharmony, neglects, violent behavior, illness and death. This study's findings highlight the importance of producing comprehensive and in-depth knowledge in search of to identify vulnerable groups and to develop participatory solutions.

Cárie dentária na América do Sul: realidade entre escolares do Brasil e Argentina / Dental caries in South America: reality among schoolchildren from Brazil and Argentina

Objetivo: este estudo transversal multicêntrico objetivou determinar a proporção de cárie dentária, sua gravidade e atividade em escolares brasileiros e argentinos. Métodos: a amostra foi composta por escolares selecionados por conveniência, 406 do Brasil (Belo Horizonte - MG) e 241 da Argentina (Córdoba-Cba). Os dados foram coletados por seis dentistas previamente treinados e calibrados (kappaintra≥0,63; kappainter≥0,67). A proporção e gravidade da cárie foram medidas pelos índices ceod e CPOD. A alta experiência de cárie foi identificada pelo Significant Caries Index (SiC). A atividade de cárie foi avaliada segundo a reflexão e a textura da superfície (Nyvad et al., 1999) e o Índice de Cuidados (O/CPO*100) foi mensurado. Resultados: a proporção de livres de cárie (ceod e CPOD = 0) no Brasil foi de 45,7% e 19,9% na Argentina. O ceod foi de 1,48 (IC95%: 1,26-1,71) e 2,38 (IC95%: 2,0-2,72) entre escolares do Brasil e da Argentina, respectivamente. Nos dois países, o componente cariado foi o mais frequente. Entre os indivíduos com experiência de cárie (ceod > 1 e/ou CPOD > 1), a atividade de cárie esteve presente em 77,5% das crianças examinadas no Brasil e em 26,4% na Argentina. No grupo SiC, o CPOD foi de 2,20 (IC95%: 1,95-2,20) no Brasil e 2,17 (IC95%: 1,91-2,43) na Argentina, e o ceod no Brasil foi de 3,37 (3,01-3,72) e na Argentina 5,56 (5,04-6,07). O Índice de Cuidados foi baixo. Conclusão: em ambos os países, a proporção de crianças com experiência de cárie foi alta. Concentração de carga e atividade de cárie foi encontrada em grupos de polarização. Cabe ressaltar que a cárie dentária na dentição decídua é um problema relevante que necessita de esforços direcionados em ambos os países.

Objective: This multicentric cross-sectional study aimed to determine the proportion of dental caries, its' severity and activity among Brazilian and Argentines schoolchildren. Methods: The sample was selected by convenience and comprised of 406 schoolchildren from Brazil (Belo Horizonte-MG) and 241 in Argentina (Córdoba-Cba). Data were collected by six previously trained and calibrated dentists (kappaintra≥0.63; kappainter≥0.67). The proportion and severity of dental caries were measured by dmft and DMFT index. The high caries experiences was identified using Significant Caries Index (SiC). The caries activity was evaluated according to the reflection and texture of the surface (Nyvad et al., 1999) and the Care Index (O/CPO * 100) was measured. Results: The caries free (dmft and DMFT = 0) in Brazil was 45.7% and 19.9% in Argentina. The dmft was 1.48 (95% CI: 1.26-1.71) and 2.38 (95% CI: 2.0-2.72) among schoolchildren in Brazil and Argentina, respectively. In both countries, decayed component was the most frequent observed. Among subjects with caries experience (dmft > 1 and / or DMFT > 1) the caries activity was present in 77.5% of the children examined in Brazil and 26.4% in Argentina. In SiC group, DMFT was 2.20 (95% CI: 1.95-2.20) in Brazil and 2.17 (95% CI: 1.91-2.43) in Argentina and dmft in Brazil was 3.37 (3.01-3.72) and in Argentina was 5.56 (5.04-6.07). The Care Index was low. Conclusions: In both countries, the proportion of children with caries experience was high. Concentration of burden and caries activity was found in polarization' groups. It is noteworthy that caries in the primary dentition is a relevant problem that needs targeted efforts in both countries.

Occurrence of violence in the elderly and its associated factors / La ocurrencia de violencia en ancianos y sus factores asociados / A ocorrência da violência em idosos e seus fatores associados

ABSTRACT Objective: to analyze the occurrence of violence in the elderly and its associated factors in the city of Betim, Minas Gerais. Method: cross-sectional study constituted by a population survey conducted through structured interviews. The sample was stratified by clusters and included 178 elderly people at the end. Data were analyzed by the chi-square test and was performed a Correspondence Analysis. Results: The most prevalent forms of violence were: lack of access to social rights (31%), verbal violence (22%), moral/psychological (19%), lack of care (16%), physical violence (6%), sexual (3%) and discrimination (3%). Women suffered more abuse than men and violence had greater association with the degree of depressive symptoms. Conclusion: our research has direct implication for the sectors interested in coping with violence in the elderly, especially for nurses, because it shows violence is part of a cycle with characteristic associated factors that conforms a model nested mainly in the family relationship.

RESUMEN Objetivo: analizar la ocurrencia de violencia en ancianos y sus factores asociados en la ciudad de Betim, Minas Gerais. Método: estudio transversal, constituido por encuesta poblacional realizada a través de entrevistas estructuradas. La muestra fue estratificada por conglomerados y al final, hubo 178 ancianos. Los datos fueron analizados a través del test chi-cuadrado y sometidos al Análisis de Correspondencia. Resultados: Las formas más prevalentes de violencia fueron: la falta de acceso a derechos sociales (31%), la violencia verbal (22%), moral/psicológica (19%), falta de cuidados (16%), violencia física (6%), sexual (3%) y discriminación (3%). Las mujeres sufrieron más abusos que los hombres y la asociación de la violencia con el grado de síntomas depresivos fue mayor. Conclusión: nuestra investigación trae implicación directa para los sectores interesados en el enfrentamiento de la violencia en el anciano, especialmente para los enfermeros, pues evidencia que la violencia es parte de un ciclo con factores asociados característicos que conforman un modelo anidado principalmente, en la relación familiar.

RESUMO Objetivo: analisar a ocorrência da violência em idosos e seus fatores associados em Betim, Minas Gerais. Método: estudo transversal, constituído por inquérito populacional realizado através de entrevistas estruturadas. A amostra foi estratificada por conglomerados e ao final, contou com 178 idosos. Os dados foram analisados pelo teste qui-quadrado e submetidos à Análise de Correspondência. Resultados: As formas mais prevalentes de violência foram a falta de acesso a direitos sociais (31%), a violência verbal (22%), moral/psicológica (19%), falta de cuidados (16%), violência física (6%), sexual (3%) e discriminação (3%). As mulheres sofreram mais abusos que os homens e houve maior associação com o grau de sintomas depressivos. Conclusão: nossa pesquisa traz implicação direta para os setores interessados no enfrentamento da violência no idoso, especialmente para os enfermeiros, pois evidencia que a violência faz parte de um ciclo com fatores associados característicos, conformando um modelo aninhado, principalmente, no relacionamento familiar.

Mitochondrial DNA Analysis of a Sample of Pre-Columbian Acient Remains from Norte de Santander, Colombia (Chitarera Cultural Area) / Análisis de adn mitocondrial en una muestra de restos óseos precolombinos de norte de santander, colombia (área cultural chitarera)

RESUMEN Los análisis de ADN antiguo (ADNa) han incrementado en los últimos años permitiendo conocer la diversidad genética de las poblaciones precolombinas. En Colombia, existen pocos registros arqueológicos de la población prehispánica del Norte de Santander habitada en el siglo XVI por el grupo Chitarero. Por este motivo, nos propusimos analizar la diversidad genética a partir de secuencias de la región HVRI del ADNmt y determinar sus posibles relaciones con otras comunidades tanto antiguas como contemporáneas. Se analizaron siete individuos precolombinos asociados a este grupo prehispánico, recuperados en los municipios de Cácota y Silos en el departamento de Norte de Santander de los Andes Orientales colombianos, siguiendo criterios estrictos de autenticidad para el ADNa. En todos los individuos se logró identificar el haplogrupo B caracterizado por el polimorfismo en la posición 16217C, siendo éste uno de los más frecuentes en comunidades precolombinas y contemporáneas de los Andes Suramericanos. Este hallazgo indica que este grupo poblacional se encuentra estrechamente emparentado por línea materna, con posibles índices de endogamia, con una probable densidad demográfica baja y una baja diversidad genética, similares a lo observado en comunidades pertenecientes a periodos anteriores como el Formativo. Este grupo precolombino exhibe una de las diversidades genéticas más bajas reportadas en las poblaciones pertenecientes a la familia lingüistica Chibcha. Estos resultados genéticos coinciden con los planteamientos sobre el grupo Chitarero de pertenecer a comunidades pequeñas independientes, con asentamientos dispersos, apartados unos de otros.

ABSTRACT In the last few years there has been an increase in ancient DNA (aDNA) analyses that has allowed shedding light on the diversity of pre-Columbian populations. In Colombia, there are few archaeological records belonging to the prehispanic population from Norte de Santander inhabited in the XVI century by the Chitarero. For this reason, we performed a genetic diversity analysis of the HVRI region of mtDNA in order to determine their possible relationships with other communities both ancient and contemporary. We analyzed seven pre-Columbian individuals belonging to this pre-Hispanic group, recovered from the municipalities of Cácota and Silos in the department of Norte de Santander located at the Colombian Andes, following strict authenticity criteria for aDNA. All individuals were identified as belonging to haplogroup B, characterized by the polymorphism found at position 16217C which is one of the most frequent haplogroups in pre-Columbian and contemporary communities of the South American Andes. This finding suggests that this population group was closely related through its maternal lineage, with possible inbreeding indexes, low population density and therefore low genetic diversity, similar to what is observed in communities belonging to previous periods such as the Formative period. This pre-Columbian group exhibits one of the lowest genetic diversities reported in populations belonging to the Chibcha linguistic family. These genetic results coincide with the views on the Chitarero group as belonging to small independent communities, with dispersed settlements separated among them.